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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TP53RK
All Species:
5.76
Human Site:
S140
Identified Species:
11.52
UniProt:
Q96S44
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96S44
NP_291028.3
253
28160
S140
E
K
T
P
Q
G
L
S
N
L
A
K
T
I
G
Chimpanzee
Pan troglodytes
XP_514697
253
28128
S140
E
K
T
P
Q
G
L
S
N
L
A
K
T
I
G
Rhesus Macaque
Macaca mulatta
XP_001107480
201
22218
D105
L
A
R
M
H
D
E
D
L
I
H
G
D
L
T
Dog
Lupus familis
XP_853966
302
33650
L189
E
K
T
P
Q
S
L
L
S
L
A
K
T
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q99PW4
244
27375
L131
E
K
D
P
Q
C
L
L
D
L
A
R
R
M
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425703
314
33606
L201
G
S
D
A
S
S
L
L
G
L
A
E
K
M
G
Frog
Xenopus laevis
NP_001089506
237
26742
N124
G
K
E
T
S
S
L
N
A
L
A
E
K
I
G
Zebra Danio
Brachydanio rerio
NP_001018386
231
26056
I122
L
Q
T
L
A
E
R
I
G
E
V
L
A
Q
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647948
224
25346
G117
L
E
F
C
T
R
I
G
E
I
I
G
K
M
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002300825
226
25241
D116
V
V
E
E
R
L
D
D
I
A
M
Q
I
G
D
Maize
Zea mays
NP_001146448
226
25230
D116
V
N
E
E
R
L
N
D
I
A
T
Q
I
G
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53323
261
29918
T140
P
Y
S
D
L
V
A
T
T
L
R
K
V
G
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
68.3
78.4
N.A.
83.7
N.A.
N.A.
N.A.
56.3
66
61.2
N.A.
41.5
N.A.
N.A.
N.A.
Protein Similarity:
100
100
71.9
81.1
N.A.
88.9
N.A.
N.A.
N.A.
66.2
78.2
77.4
N.A.
56.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
73.3
N.A.
53.3
N.A.
N.A.
N.A.
26.6
40
6.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
86.6
N.A.
73.3
N.A.
N.A.
N.A.
40
53.3
13.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
44.2
41.9
N.A.
N.A.
32.1
N.A.
Protein Similarity:
60.4
58.1
N.A.
N.A.
48.6
N.A.
P-Site Identity:
0
0
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
13.3
13.3
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
9
0
9
0
9
17
50
0
9
0
0
% A
% Cys:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
17
9
0
9
9
25
9
0
0
0
9
0
9
% D
% Glu:
34
9
25
17
0
9
9
0
9
9
0
17
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
0
0
0
0
17
0
9
17
0
0
17
0
25
50
% G
% His:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
9
% H
% Ile:
0
0
0
0
0
0
9
9
17
17
9
0
17
25
0
% I
% Lys:
0
42
0
0
0
0
0
0
0
0
0
34
25
0
0
% K
% Leu:
25
0
0
9
9
17
50
25
9
59
0
9
0
9
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
9
0
0
25
9
% M
% Asn:
0
9
0
0
0
0
9
9
17
0
0
0
0
0
9
% N
% Pro:
9
0
0
34
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
34
0
0
0
0
0
0
17
0
9
0
% Q
% Arg:
0
0
9
0
17
9
9
0
0
0
9
9
9
0
9
% R
% Ser:
0
9
9
0
17
25
0
17
9
0
0
0
0
0
0
% S
% Thr:
0
0
34
9
9
0
0
9
9
0
9
0
25
0
9
% T
% Val:
17
9
0
0
0
9
0
0
0
0
9
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _